Jeff applies his 25+ years of well-recognized expertise in neuroscience, drug development, and pipeline expansion to his role as chair of Sage’s Science & Technology Forum of the Board and member of our CNS Innovation Scientific Advisory Board. He most recently served as CEO at Sage from 2013 – 2020, providing his creative, innovative thinking to building one of the industry’s leading brain health product pipelines. Jeff is well-known for encouraging a pursuit of new opportunities by taking smart risks and challenging conventional wisdom. His approach is shaped by a career that encompasses one-on-one patient care, rapid advancement through corporate structures, academic accomplishments, and entrepreneurial endeavors. Before joining the Sage team, Jeff served as President of the Regenerative Medicine Division of Shire Plc and previously as Senior Vice President of Research and Development, Pharmaceuticals at Shire. Prior to Shire, he served as the Executive Vice President of ISIS Pharmaceuticals, as the Chief Medical Officer and Executive Vice President of Forest Laboratories, Inc. and in senior-level positions at Upjohn Laboratories. Jeff is a member of the board for Generation Bio and Karuna Therapeutics. He has published more than 190 scientific papers and articles, chapters, abstracts and books, and has received numerous awards.

Jeff received his B.A. from Amherst College and M.D. from Harvard Medical School. He completed a residency in psychiatry at Harvard and then served as Chief Resident in psychopharmacology at McLean Hospital, Harvard Medical School.